Mainstream Tobacco Smoke Causes Paternal Germ-Line DNA Mutation
نویسندگان
چکیده
منابع مشابه
Mainstream tobacco smoke causes paternal germ-line DNA mutation.
Despite the presence of known mutagens and carcinogens in cigarette smoke, there is currently no evidence to show that smoking, or exposure to cigarette smoke, can result in heritable genetic mutation. We show that male mice exposed to mainstream tobacco smoke (MTS) exhibit a significant increase in germ-line mutation frequency in spermatogonial stem cells. We exposed mature male mice to MTS fo...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2007
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-07-0279